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Before its mainstream surge in 2023, Ozempic was not a household name unless you had diabetes. But thanks to celebrity influence, it’s become a quick fix for those who want to lose excess pounds. 

Some people have even posted before-and-after photos of themselves since making the medication a part of their lives. Here are a few examples from those who seem to have no qualms about the “Ozempic face.” 

People will have varying opinions about this new health trend, and we would like to hear yours in the comments.

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    One of the first times Ozempic was mentioned in a wider public sphere was during the Academy Awards in 2023, when host Jimmy Kimmel looked around a room filled with Hollywood A-listers and quipped, “When I look around this room, I can't help but wonder: Is Ozempic right for me?”

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    At the time, Kimmel described the medication as the “worst-kept secret in Hollywood” as some of the biggest names began admitting to using it. 

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    Since it became a health trend that many regular folks soon followed, the “Ozempic face” also drew attention. While it’s not a medically recognized condition, it has become a cause for concern. 

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    In a nutshell, the Ozempic face is the result of sudden facial fat loss, often characterized by sunken cheeks, accentuated wrinkles, and sagging skin.

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    The term “Ozempic face” has become problematic in itself, according to medical professionals. As Mayo Clinic endocrinologist Dr. Aoife Egan states, it makes light of the underlying conditions for which the medication is intended, namely diabetes and obesity. 

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    “People with obesity have been referred to in various derogatory terms. This is just another way that has the potential to cause harm to a vulnerable group of people,” Dr. Egan said.

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    The facial transformations brought on by Ozempic use may give the person a superficial boost. However, skin sagging also accelerates signs of aging, such as fine lines. 

    It’s why experts like endocrinologist Dr. Vinni Makin advise against rapid weight loss of any kind.

    #13

    Man wearing sunglasses and a yellow polo shirt showing dramatic facial changes after Ozempic journey by the sea.

    jholden3 Report

    Emma London
    Community Member
    9 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    You can see the better confidence in the after picture.

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    #15

    Side-by-side photos showing dramatic facial changes from the Ozempic face journey in before and after comparison.

    Acinnamontaste Report

    Lil be lil
    Community Member
    1 hour ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    I like her before face better, beautiful.

    “You can also minimize these side effects by using your medication in combination with a healthy diet and exercise regimen,” Dr. Makin told the Cleveland Clinic

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    Dr. Makin says cosmetic fillers and skin-tightening procedures are also viable options for minimizing wrinkles and sagging skin.

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    #18

    Side-by-side photos showing dramatic facial changes during an Ozempic journey with noticeable skin and weight differences.

    ChelseaMarie Report

    Lil be lil
    Community Member
    59 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    Now she can be the Girly girl! Wonderful.

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    #22

    Side-by-side photos of a woman showing dramatic facial changes during her Ozempic journey with noticeable slimming.

    Vanessa and Lawrence Report

    Lil be lil
    Community Member
    57 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    That is not how your eyebrows should be

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    #31

    Before and after photos showing dramatic facial changes during an Ozempic journey, highlighting Ozempic face effects.

    kaseytwyman Report

    Lil be lil
    Community Member
    1 hour ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    Usually the bad Ozempic faces are older women like Sharon Osbourne, but I will say it do much for Kelly either.

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    #46

    Side-by-side photos showing dramatic facial changes from an Ozempic journey with noticeable slimming effects.

    𝑴𝒊𝒄𝒉𝒆𝒍𝒆 ᥫ᭡ Report

    Lil be lil
    Community Member
    50 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    Gee, I think weight loss makes your eyes bigger too!

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    #49

    Before and after photos showing dramatic facial changes from an Ozempic journey between March and December 2025.

    Bliss Acres Farm Report

    Emma London
    Community Member
    6 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    It's also the camera angle, but looking great!

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    #60

    Side-by-side photos showing dramatic facial changes in a woman during her Ozempic journey with noticeable weight loss.

    therealwitchymommie Report

    Lil be lil
    Community Member
    53 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    Please, don't go into MAGAS face nowl

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    #71

    Before and after portraits of a woman showing dramatic facial changes during her Ozempic journey with noticeable weight loss effects.

    Lynsay_Reilly Report

    Lil be lil
    Community Member
    43 minutes ago Created by potrace 1.15, written by Peter Selinger 2001-2017

    The best of the bunch transformation.. Good looking girl.

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    #74

    Side-by-side before and after photos showing dramatic facial changes from the Ozempic face transformation journey.

    "I'll take Ozempic Face"

    lesliestag Report

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