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My strategy in crazy 8's and uno is to save up wildcards or 8s and keep at least 2 in my hand until they're the only cards I have left, so when people start actively trying to thwart me it's too late. I win with this sometimes but also sometimes I'll be down to 1 or 2 non-wild cards but I have to draw or use my wild cards against my rules and I end up drawing half the deck.